Thrombopoietin receptor agonist, splenectomy and intravenous immunoglobulin for immune thrombocytopaenia with systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Successful Treatment with Thrombopoietin Receptor Agonist in Avoiding Splenectomy for Patients with Chronic Refractory Immune Thrombocytopenia
BACKGROUND Chronic immune thrombocytopenia (ITP) is a condition associated with significant morbidity; however the management options are often unsatisfactory with a portion of patients exhibiting a refractory-relapsing disease path despite various lines of treatment including splenectomy. As a thrombopoietin receptor agonist, eltrombopag (GlaxoSmithKline, Australia) provides a novel treatment ...
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Background The prevalence of autoimmune thrombocytopenia in juvenile systemic lupus erythematosus (JSLE) ranges from 7–52% (mean 14,5%) but profound rates (<50,000/mL) are uncommon. Although the exact mechanism is unknown, the spleen has been implicated either as the source of antiplatelet antibodies or the site of sensitized platelets destruction. Splenectomy is rarely indicated due to the inc...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2018
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/key072